Which enzyme joins okazaki fragments

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Join Clutch Prep Get a better grade with hundreds of hours of expert tutoring videos for your textbook Continue Continue OR Password must contain at least one uppercase letter, a number and a specific symbol. Problem : The enzyme that joins Okazaki fragments is: a.

Primase b. DNA polymerase c. Nucleosomes are spaced at intervals of about nucleotides pairs along the DNA strand , which may explain why new Okazaki fragments are synthesized on the lagging strand at intervals of nucleotides in eukaryotes, instead of nucleotides as in bacteria. This is why DNA replication is described as semi-conservative, half of the chain is part of the original DNA molecule, half is brand new. Following replication the new DNA automatically winds up into a double helix.

Each end of the bubble is a replication fork , a Y-shaped junction where double-stranded DNA is separated into two single strands. Proteins called single-strand binding proteins coat the separated strands of DNA near the replication fork , keeping them from coming back together into a double helix. Helicases are enzymes that bind and may even remodel nucleic acid or nucleic acid protein complexes.

Watson and Crick used stick-and-ball models to test their ideas on the possible structure of DNA. Other scientists used experimental methods instead. Replication of DNA is based on making strands complementary to the two strands produced when the double-stranded DNA is unwound. The four bases include two purines and two pyrimidines. Semiconservative replication would produce two copies that each contained one of the original strands and one new strand.

Conservative replication would leave the two original template DNA strands together in a double helix and would produce a copy composed of two new strands containing all of the new DNA base pairs. When we say that DNA replication is semiconservative , we mean that : Both strands get shortened at opposite ends during replication. Instant Video Solutions. Request OTP. Updated On: Share This Video Whatsapp. Text Solution.

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